Dehydro Nifedipine ( —— )

产品货号. M34871 CAS No. 67035-22-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Dehydro Nifedipine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Dehydro Nifedipine (BAY-b 4759) is the main metabolite of nifedipine in human plasma. Dehydro Nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 μM. Nifedipine is a calcium channel blocker used in the treatment of hypertension and angina. Dehydronifedipine is formed when it is metabolized by cytochrome P450 (CYP) isomers CYP3A4 and CYP3A5.
产品描述

Dehydro Nifedipine (BAY-b 4759) is the main metabolite of nifedipine in human plasma. Dehydro Nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 μM. Nifedipine is a calcium channel blocker used in the treatment of hypertension and angina. Dehydronifedipine is formed when it is metabolized by cytochrome P450 (CYP) isomers CYP3A4 and CYP3A5.
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Drug Metabolite
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